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Blog Post

Exploring New Frontiers in Parkinson’s Research: Our Journey

December 3, 2024
·
2 min read
QuantalX Neuroscience

By Noa Zifman, VP Clinical & Regulatory

I am honored to share an incredible milestone in our research journey: the publication of our comprehensive work on occipital network involvement in Parkinson’s disease in Nature NPJ Parkinson’s Disease. This publication not only represents the culmination of extensive effort but also underscores the transformative potential of our Delphi technology in advancing neurological research and patient care.

The Significance of This Study

Our research delves into the early stages of Parkinson’s disease, aiming to address critical gaps in diagnosis and treatment. By utilizing TMS-evoked potentials (TEPs), we demonstrated how Delphi-MD’s unique technology can accurately differentiate between subtypes of Parkinson’s disease within the first five years from diagnosis. This differentiation is pivotal for tailoring treatment strategies and improving patient outcomes.
The findings also highlight the involvement of the occipital network, providing new insights into underlaying neurophysiological mechanisms that manifest as Parkinson’s clinical variability. These discoveries pave the way for earlier, more precise interventions, a goal that has always been at the heart of our work, at QuantalX Neuroscience.

What This Means for Neurological Care

This Nature Publishing Journal (NPJ) Parkinson’s Disease publication is more than just an academic achievement. It represents a step forward for the entire neurological community, bringing us closer to a future where conditions like Parkinson’s can be classified and managed earlier and more effectively, using Delphi-MD.

Looking Ahead

This achievement marks a significant milestone in advancing brain health research and reflects our ongoing commitment to pushing the boundaries of neurodiagnostics. I’m deeply grateful to Prof. Anat Mirelman, Dr. Avner Taler, and Dr. Inbal Maidan, from the Laboratory of Early Markers of Neurodegeneration (LEMON), Neurological Institute, Tel Aviv Sourasky Medical Center, Israel, who led the study.

A special thank you to Prof. Mark Hallett for his invaluable contribution. With Delphi-MD providing insights into neurophysiological brain function, we look forward to continuing our efforts to improve early detection and enhance patient care. This collaboration truly demonstrates the power of teamwork in transforming the future of brain health.

For more details, read the full study here.

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*All clinical interpretations of Delphi-MD™ assessments must be made by qualified healthcare professionals within the context of a full patient evaluation. The Delphi-MD™ system is intended to elicit, record, and analyze TMS-evoked brain potentials (TEPs) and provide quantitative output parameters compared against a normative reference database limited to ages 50–75. Adverse events during or after evaluation may include headache, nausea, dizziness, fatigue, insomnia, anxiety/agitation, back or neck pain, vomiting, tinnitus, migraine aura, and abnormal sensations. Delphi-MD™ is not intended to be relied upon solely to make or confirm a diagnosis. For more information, refer to the Delphi-MD™ user manual.