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Clinical Research

Clinical Research

Delphi-Research provides pharmaceutical companies and academic institutions with robust, reproducible, and scalable electrophysiological endpoints to drive clinical trials forward.

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Standardized Endpoints

Evaluate target engagement with reproducible network biomarkers.

Trial Optimization

Stratify cohorts more precisely and cut variance between sites.

Scalable Deployment

Run identical point-of-care testing across every trial site.

Data-Rich Analytics

Access raw electrophysiological data for deeper exploration.

HOW IT WORKS

From pulse to report

Delphi-Research combines focused transcranial magnetic stimulation with synchronised EEG recording, then analyses the evoked responses automatically. Every session follows the same protocol, so results stay comparable across visits, sites and cohorts.

  • Focused magnetic pulses are delivered to predefined cortical targets
  • TMS-evoked potentials are recorded across the scalp and processed automatically
  • Network measures are compared against an age-correlated normative database
  • A quantitative report is produced at the point of care, with no manual scoring
DRUG DEVELOPMENT

Endpoints for trials

Delphi-Research offers pharmaceutical researchers a powerful tool to evaluate the pharmacodynamic effects of CNS-targeted therapies. By delivering accurate, repeatable data on brain network function, Delphi-Research can aid in patient selection, streamline efficacy evaluation, enhance target engagement, and potentially reduce reliance on delayed or subjective behavioral endpoints. Its non-invasive, rapid assessment format helps accelerate clinical trials, supports long-term medication monitoring, and optimizes protocols.

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*All clinical interpretations of Delphi-MD™ assessments must be made by qualified healthcare professionals within the context of a full patient evaluation. The Delphi-MD™ system is intended to elicit, record, and analyze TMS-evoked brain potentials (TEPs) and provide quantitative output parameters compared against a normative reference database limited to ages 50–75. Adverse events during or after evaluation may include headache, nausea, dizziness, fatigue, insomnia, anxiety/agitation, back or neck pain, vomiting, tinnitus, migraine aura, and abnormal sensations. Delphi-MD™ is not intended to be relied upon solely to make or confirm a diagnosis. For more information, refer to the Delphi-MD™ user manual.